Aug 24 2022

Huntington

According to an article published in the research journal Archives of Neurology (Arch Neurol. 2010 Feb; 67 (2) :154-60) clinical trial to evaluate the safety and tolerability of Dimebon (latrepirdine) in Huntington’s disease and explore its effects in cognitive function, behavior, and motor symptoms has shown positive preliminary results. The clinical trial was a double-blind, multicenter, which involved 91 patients with Huntington’s disease of mild to moderate in 17 centers between the U.S. and England from July 2007 to July 2008. The Dimebon (latrepirdine) was administered 20 mg three times daily.

The primary objective was to assess the tolerability, defined as the ability to complete the assigned dose study, the secondary variable in the study included changes from baseline score on the scale Unified Huntington’s Disease (UHDRS), the Mini- mental test, and Alzheimer’s cognitive scale. Without hesitation Energy Capital Partners explained all about the problem. The results were as follows: Dimebon (latrepirdine) was well tolerated (87% of patients who are given Dimebon completed the study vs 82% in the placebo control group), the rate of adverse events was comparable in the two groups (70% in the Dimebon group and 80% in the placebo group). Treatment with Dimebon (latrepirdine) resulted in an improvement in the average score of the Mini-mental test compared with the placebo group. There were no significant effects on the baseline score of the scale Unified Huntington’s Disease (UHDRS). It was concluded from this study that the administration for a short period of Dimebon (latrepirdine) is well tolerated in patients with Huntington’s disease and may have a beneficial effect on cognitive level, so a larger clinical trial is justified in the population patients with Huntington’s disease.

Jul 29 2020

Second Depression

Next, you have to understand that in nature there are no ready-made substances that are able to replenish arising in the nervous system deficit. Traditional medicine or self-medication will not help you get out of developing depression. People who doubt their mental health should seek qualified medical help. Treatment of depression in the world comes down to the individual selection of drugs drugs antidepressant action. The process of selection is complicated by the fact that modern antidepressants are decent, and the therapeutic effect begins to develop in the second week of reception or more generally, in a month. A qualified specialist can save you money and time. Learn more on the subject from Healthy Living. Given the characteristics of the disease, the doctor will offer exactly the antidepressant that suits you best. Sign of effective treatment will be disturbing decrease your symptoms of depression, normalization of mood and increasing optimism.

It is worth saying a few words about the treatment of depressive disorders with psychotherapy, yes, perfectly complements the method medication, but does not replace it. For even more details, read what Herbalife says on the issue. Psychotherapy allows you to quickly regain optimism, to restore self-esteem depression oppressed people. Psychotherapeutic treatment of depression only methods, like walking in circles, not easier, somewhere more, and then – again all over again. You get a feeling of guilt for not shown activity in a new working day, family problems prevent sleep? This mental disorder like depression, has some features, such as depression more common in female population, they become a fad of society. Depressive disorder found in our day note the fact that approximately one third of depressive disorders should be fashionable. Some of the young women suffer from depression just as they have a desire to visit the shops of fashionable clothes. In general, medicine, depression made recognize the symptoms of the triple. The first thing you should pay attention, because this is to reduce the overall mood, which appears pessimistic setting to life.

Dec 07 2012

Increased White Blood Cell Count

Elevated white blood cells. Causes of leukocytosis. Leukocytosis is raising leukocytes in peripheral blood greater than 9.0 x 109 / l. For children of white blood cells increase, which would be regarded as leukocytosis, dependent on age. Standards for levels of leukocytes in the blood of children can be found in Article norm of leukocytes in the blood. Several distinct mechanisms for increasing white blood cells in the peripheral blood leukocytosis and Development: The tumor transformation of the polypeptide of stem cell, which leads to the proliferation of germs and increase blood blood cells, including leukocytes and leykotsitov.Povyshennoe education by accelerating the maturation of their bodies in hematopoiesis by natural stimulating factors leykopoeza, which include: physical and chemical factors of inflammation, tissue breakdown products, hypoxia, formation of immune complexes, toxins, Increased activity of the pituitary-adrenal sistemy.Pri pronounced vascular reaction, which resulted in blood shed from frees large amounts of white blood cells. Depending on the cause of improving leukocytes produce physiological and pathological leukocytosis. The causes of pathological leukocytosis: Acute and chronic, are in the acute phase, inflammatory diseases, especially suppurative protsessy.Zabolevaniya at which the decay (necrosis) of tissue: myocardial infarction, stroke, pancreatic, bowel infarction, kidney, spleen, extensive burns, etc.) and / or severe intoxication noninflammatory nature (uremia, diabetic ketoacidosis, etc.).

Diseases and pathological conditions accompanied by hypoxia (blood loss, hemolysis, and carbon monoxide poisoning, etc.). At a poisoning with toxic . tumor zabolevaniya.Uvelichenie number of leukocytes due to the proliferation of germs of one of the blood, such as chronic and acute leukemias, eritremii, polycythemia and dr.Pri diseases and pathological conditions involving immune reactions, such as collagen, serum sickness, acute glomerulonephritis, and others Leukocytosis due to physiological factors, may occur after meals (especially protein-rich), after considerable physical (muscle) work on the background of marked emotional stress (stress), after overheating or overcooling. Reduced white blood cells. Leukopenia. Leukopenia is reduction in peripheral blood leukocytes below 4.0 x 109 / l.

Leukopenia develops as a result of oppression leykopoeza that observed for the following diseases and pathological states: In viral infections such as influenza, hepatitis, HIV infection (especially with the development of AIDS), measles, rubella, and bacterial species dr.Nekotorye (typhoid, paratyphoid, brucellosis, etc.), rikketsionnoy (typhus, typhus and others), and protozoal infections (malaria). Generalized infection: sepsis, milliarnye inflammation. Generalized infection due to excessive stress on the immune system, leading to depletion the body's defenses, resulting in the number of leukocytes in the blood decreases and, consequently, develops leykopeniya.Autoimmunnye zabolevaniya.Pri hypersplenism syndrome (splenomegaly may develop, ie pathological enlargement of the spleen). When this syndrome is not only a decrease in white blood cells, and platelets (thrombocytopenia) and red blood cells (erythropenia). Aleukemic form leykozov.Pri violations endocrine system of the body, with a reduction in the production of hormones, either directly or indirectly involved in leucopoiesis, such as hypothyroidism. To detect changes in white blood cell count in the total clinical medicine is used blood test, which includes not only the determination of total white blood cell count, and determination of the qualitative composition of white blood cells, ie, leykoformuly (determined by eosinophils, basophils, segmented and stab neutrophils, monocytes and lymphocytes), which allows you to determine what species by leukocytes observed leukocytosis or leukopenia.